Found this old True West Moment this morning, while looking for something else.
The Real Scourge of The Old West
As dangerous as the Wild West was, all the battles and armed conflicts paled when compared to the deadly foe of smallpox. An airborne scourge for centuries, smallpox arrived in the New World with the Spanish in 1509 and spread from the Caribbean to the North American Native American population where it decimated entire tribes. Although vaccination campaigns began in the early 1800s, the disease was not eradicated until the 1970s.
"The only new thing in this world is the history you don't know."